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The purpose of the chapter is to describe practice and quality standards for handling hazardous drugs in healthcare settings to promote patient safety, worker safety, and environmental protection

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An increase in dosage to the maximum of 522 mg/day, given as a single dose, may be considered for patients in whom no clinical improvement is noted after several weeks of treatment at 348 mg/day.

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A prescription drug recall may be ordered when problems appear on a large scale.

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